Subretinal Fibrosis in HARBOR Varies by Choroidal Neovascularization Subtype

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Subretinal choroidal neovascularization associated with choroidal nevus.

PURPOSE Evaluation of a large series of choroidal nevi inducing the formation of a neovascular membrane in order to more clearly define the clinical presentation and to evaluate the efficacy of various treatment options. METHOD Retrospective study of 22 clinical cases. RESULTS All nevi were situated in the posterior choroid. They had a mean diameter of 3.8 mm and a mean thickness of 1.4 mm....

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Choroidal neovascularization (CNV) is a critical pathogenesis in age-related macular degeneration (AMD), the most common cause of blindness in developed countries. To date, the precise molecular and cellular mechanisms underlying CNV have not been elucidated. Platelet-activating factor (PAF) has been previously implicated in angiogenesis; however, the roles of PAF and its receptor (PAF-R) in CN...

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ژورنال

عنوان ژورنال: Ophthalmology Retina

سال: 2020

ISSN: 2468-6530

DOI: 10.1016/j.oret.2020.02.012